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The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
The mouse hippocampal cell line HT22 is an excellent model for studying the consequences of endogenous oxidative stress. Addition of extracellular glutamate depletes the cells of glutathione (GSH) by blocking the glutamate−cystine antiporter system x(c)(−). GSH is the main antioxidant in neurons and...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564003/ https://ncbi.nlm.nih.gov/pubmed/23348584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.216 |
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