Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax

Resistance to TRAIL (TNF-related apoptosis-inducing ligand)- induced apoptosis limits its therapeutic use. Different strategies of TRAIL sensitization and a dependency on Bax have been reported, but common principles of TRAIL resistance and the way of Bax activation remained poorly understood. Apply...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Berger, A, Quast, S-A, Plötz, M, Kammermeier, A, Eberle, J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563986/
https://ncbi.nlm.nih.gov/pubmed/23348591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.198
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