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CCR2 deficiency prevents neuronal dysfunction and cognitive impairments induced by cranial irradiation

Cranial irradiation can lead to long-lasting cognitive impairments in patients receiving radiotherapy for the treatment of malignant brain tumors. Recent studies have suggested inflammation as a major contributor to these deficits; we determined if the chemokine receptor 2 (CCR2) was a mediator of c...

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Bibliographic Details
Main Authors: Belarbi, Karim, Jopson, Timothy, Arellano, Carla, Fike, John R., Rosi, Susanna
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563875/
https://ncbi.nlm.nih.gov/pubmed/23243025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2989
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