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Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay

During animal development, SDF1 simultaneously guides various cell types to different targets. As many targets are in close proximity to one another, it is unclear how the system avoids mistargeting. Zebrafish trigeminal sensory neurons express the SDF1 receptor Cxcr4b and encounter multiple SDF1 so...

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Detalhes bibliográficos
Main Authors: Lewellis, Stephen W., Nagelberg, Danielle, Subedi, Abhi, Staton, Alison, LeBlanc, Michelle, Giraldez, Antonio, Knaut, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563679/
https://ncbi.nlm.nih.gov/pubmed/23382464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207099
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