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Mechanism of the Antiviral Activity Resulting from Sequential Administration of Complementary Homopolyribonucleotides to Cell Cultures

The antiviral activity of the double-stranded complex poly(rI) · poly(rC) in cell culture was restored or even surpassed if the constituent homopolymers were administered separately. Poly(rI) primed the cells for the antiviral activity of poly(rC) and poly(rC) primed for poly(rI), but neither poly(r...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: De Clercq, Erik, De Somer, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4337160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.9.5.721-731.1972
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