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Astrocytic Ca(2+) signals are required for the functional integrity of tripartite synapses

BACKGROUND: Neuronal activity alters calcium ion (Ca(2+)) dynamics in astrocytes, but the physiologic relevance of these changes is controversial. To examine this issue further, we generated an inducible transgenic mouse model in which the expression of an inositol 1,4,5-trisphosphate absorbent, “IP...

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Detalhes bibliográficos
Main Authors: Tanaka, Mika, Shih, Pei-Yu, Gomi, Hiroshi, Yoshida, Takamasa, Nakai, Junichi, Ando, Reiko, Furuichi, Teiichi, Mikoshiba, Katsuhiko, Semyanov, Alexey, Itohara, Shigeyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563617/
https://ncbi.nlm.nih.gov/pubmed/23356992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-6
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