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Astrocytic Ca(2+) signals are required for the functional integrity of tripartite synapses

BACKGROUND: Neuronal activity alters calcium ion (Ca(2+)) dynamics in astrocytes, but the physiologic relevance of these changes is controversial. To examine this issue further, we generated an inducible transgenic mouse model in which the expression of an inositol 1,4,5-trisphosphate absorbent, “IP...

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Hlavní autoři: Tanaka, Mika, Shih, Pei-Yu, Gomi, Hiroshi, Yoshida, Takamasa, Nakai, Junichi, Ando, Reiko, Furuichi, Teiichi, Mikoshiba, Katsuhiko, Semyanov, Alexey, Itohara, Shigeyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563617/
https://ncbi.nlm.nih.gov/pubmed/23356992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-6
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