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ZnT8-Specific CD4(+) T Cells Display Distinct Cytokine Expression Profiles between Type 1 Diabetes Patients and Healthy Adults

Determination of antigen-specific T cell repertoires in human blood has been a challenge. Here, we show a novel integrated approach that permits determination of multiple parameters of antigen-specific T cell repertoires. The approach consists of two assays: the Direct assay and the Cytokine-driven...

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Main Authors: Chujo, Daisuke, Foucat, Emile, Nguyen, Thien-Son, Chaussabel, Damien, Banchereau, Jacques, Ueno, Hideki
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563599/
https://ncbi.nlm.nih.gov/pubmed/23390544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055595
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