Targeting of ICAM-1 on vascular endothelium under static and shear stress conditions using a liposomal Gd-based MRI contrast agent

BACKGROUND: The upregulation of intercellular adhesion molecule-1 (ICAM-1) on the endothelium of blood vessels in response to pro-inflammatory stimuli is of major importance for the regulation of local inflammation in cardiovascular diseases such as atherosclerosis, myocardial infarction and stroke....

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Main Authors: Paulis, Leonie EM, Jacobs, Igor, van den Akker, Nynke M, Geelen, Tessa, Molin, Daniel G, Starmans, Lucas WE, Nicolay, Klaas, Strijkers, Gustav J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563567/
https://ncbi.nlm.nih.gov/pubmed/22716048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-10-25
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