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Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies
BACKGROUND: Proper expression and functioning of transcription factors (TFs) are essential for regulation of different traits and thus could be crucial for the development of complex diseases. Subjects with Down syndrome (DS) have a higher incidence of acute lymphoblastic leukemia (ALL) while solid...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563522/ https://ncbi.nlm.nih.gov/pubmed/23343470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-12 |
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