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Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases
The human c-mpl gene (MPL) plays an important role in the development of megakaryocytes and platelets as well as the self-renewal of haematopoietic stem cells. However, numerous MPL mutations have been identified in haematopoietic diseases. These mutations alter the normal regulatory mechanisms and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563459/ https://ncbi.nlm.nih.gov/pubmed/23351976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-11 |
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