α(2)-Adrenoceptor Functionality in Postmortem Frontal Cortex of Depressed Suicide Victims

BACKGROUND: Alterations in brain density and signaling associated with monoamine receptors are believed to play a role in depressive disorders. This study evaluates the functional status of α(2A)-adrenoceptors in postmortem frontal cortex of depressed subjects. METHODS: G-protein activation and inhi...

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Main Authors: Valdizán, Elsa M., Díez-Alarcia, Rebeca, González-Maeso, Javier, Pilar-Cuéllar, Fuencisla, García-Sevilla, Jesús A., Meana, J. Javier, Pazos, Angel
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562997/
https://ncbi.nlm.nih.gov/pubmed/20864091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.07.023
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