Molecular Profiling of Prostatic Acinar Morphogenesis Identifies PDCD4 and KLF6 as Tissue Architecture–Specific Prognostic Markers in Prostate Cancer

Histopathological classification of human prostate cancer (PCA) relies on the morphological assessment of tissue specimens but has limited prognostic value. To address this deficiency, we performed comparative transcriptome analysis of human prostatic acini generated in a three-dimensional basement...

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Detalhes bibliográficos
Principais autores: Li, Chi-Rong, Su, Jimmy J.-M., Wang, Wei-Yu, Lee, Michael T.-L., Wang, Ting-Yun, Jiang, Kuan-Ying, Li, Chein-Feng, Hsu, Jong-Ming, Chen, Chi-Kuan, Chen, Marcelo, Jiang, Shih-Sheng, Weaver, Valerie M., Tsai, Kelvin K.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562735/
https://ncbi.nlm.nih.gov/pubmed/23219426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.10.024
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