Three-Dimensional mRNA Measurements Reveal Minimal Regional Heterogeneity in Esophageal Squamous Cell Carcinoma

The classic tumor clonal evolution theory postulates that cancers change over time to produce unique molecular subclones within a parent neoplasm, presumably including regional differences in gene expression. More recently, however, this notion has been challenged by studies showing that tumors main...

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Detalhes bibliográficos
Main Authors: Yan, Wusheng, Shih, Joanna, Rodriguez-Canales, Jaime, Tangrea, Michael A., Player, Audrey, Diao, Lixia, Hu, Nan, Goldstein, Alisa M., Wang, Jing, Taylor, Philip R., Lippman, Scott M., Wistuba, Ignacio I., Emmert-Buck, Michael R., Erickson, Heidi S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562732/
https://ncbi.nlm.nih.gov/pubmed/23219752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.10.028
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