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Insulin-Like Growth Factor 1 Mitigates Hematopoietic Toxicity after Lethal Total Body Irradiation

PURPOSE: To investigate whether and how insulin-like growth factor 1 (IGF-1) mitigates hematopoietic toxicity after total body irradiation. METHODS AND MATERIALS: BALB/c mice were irradiated with a lethal dose of radiation (7.5 Gy) and treated with IGF-1 at a dose of 100 μg/dose intravenously once a...

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Autores principales: Zhou, Dunhua, Deoliveira, Divino, Kang, Yubin, Choi, Seung S., Li, Zhiguo, Chao, Nelson J., Chen, Benny J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562560/
https://ncbi.nlm.nih.gov/pubmed/23021438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.08.014
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