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Signalling properties of inorganic polyphosphate in the mammalian brain

Inorganic polyphosphate is known to be present in the mammalian brain at micromolar concentrations. Here we show that polyphosphate may act as a gliotransmitter, mediating communication between astrocytes. It is released by astrocytes in a calcium-dependent manner and signals to neighbouring astrocy...

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Detalhes bibliográficos
Main Authors: Holmström, Kira M., Marina, Nephtali, Baev, Artyom Y., Wood, Nicholas W., Gourine, Alexander V., Abramov, Andrey Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562455/
https://ncbi.nlm.nih.gov/pubmed/23322050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2364
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