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Ablation of Smooth Muscle Caldesmon Affects the Relaxation Kinetics of Arterial Muscle

Smooth muscle caldesmon (h-CaD) is an actin- and myosin-binding protein that reversibly inhibits the actomyosin ATPase activity in vitro. To test the function of h-CaD in vivo, we eliminated its expression in mice. The h-CaD-null animals appeared normal and fertile, although the litter size was smal...

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Detalhes bibliográficos
Main Authors: Guo, Hongqiu, Huang, Renjian, Semba, Shingo, Kordowska, Jolata, Huh, Yang Hoon, Khalina-Stackpole, Yana, Mabuchi, Katsuhide, Kitazawa, Toshio, Wang, C.-L. Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562409/
https://ncbi.nlm.nih.gov/pubmed/23149489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1178-8
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