Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler

Chromatin remodelers can either organize or disrupt nucleosomal arrays, yet the mechanisms specifying these opposing actions are not clear. Here, we show that the outcome of nucleosome sliding by Chd1 changes dramatically depending on how the chromatin remodeler is targeted to nucleosomes. Using a C...

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Bibliographische Detailangaben
Hauptverfasser: Patel, Ashok, Chakravarthy, Srinivas, Morrone, Seamus, Nodelman, Ilana M., McKnight, Jeffrey N., Bowman, Gregory D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Gene Regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561990/
https://ncbi.nlm.nih.gov/pubmed/23275572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1440
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