Systematic screens of proteins binding to synthetic microRNA precursors

We describe a new, broadly applicable methodology for screening in parallel interactions of RNA-binding proteins (RBPs) with large numbers of microRNA (miRNA) precursors and for determining their affinities in native form in the presence of cellular factors. The assays aim at identifying pre-miRNAs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Towbin, Harry, Wenter, Philipp, Guennewig, Boris, Imig, Jochen, Zagalak, Julian A., Gerber, André P., Hall, Jonathan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Methods Online
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561989/
https://ncbi.nlm.nih.gov/pubmed/23221640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1197
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