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Systematic screens of proteins binding to synthetic microRNA precursors
We describe a new, broadly applicable methodology for screening in parallel interactions of RNA-binding proteins (RBPs) with large numbers of microRNA (miRNA) precursors and for determining their affinities in native form in the presence of cellular factors. The assays aim at identifying pre-miRNAs...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561989/ https://ncbi.nlm.nih.gov/pubmed/23221640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1197 |
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