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Elucidating combinatorial histone modifications and crosstalks by coupling histone-modifying enzyme with biotin ligase activity

Histone post-translational modifications (PTMs) often form complex patterns of combinations and cooperate to specify downstream biological processes. In order to systemically analyse combinatorial PTMs and crosstalks among histone PTMs, we have developed a novel nucleosome purification method called...

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Autori principali: Lau, Priscilla Nga Ieng, Cheung, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561940/
https://ncbi.nlm.nih.gov/pubmed/23258705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1247
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