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Regulation of dendritic cell activation by microRNA let-7c and BLIMP1

Mice with a DC-specific deletion of the transcriptional repressor B lymphocyte–induced maturation protein-1 (Blimp1) exhibit a lupus-like phenotype, secondary to enhanced DC production of IL-6. Here we explored further phenotypic changes in Blimp1-deficient DCs, the molecular mechanism underlying th...

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Bibliografske podrobnosti
Main Authors: Kim, Sun Jung, Gregersen, Peter K., Diamond, Betty
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561813/
https://ncbi.nlm.nih.gov/pubmed/23298838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64712
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