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Regulation of dendritic cell activation by microRNA let-7c and BLIMP1
Mice with a DC-specific deletion of the transcriptional repressor B lymphocyte–induced maturation protein-1 (Blimp1) exhibit a lupus-like phenotype, secondary to enhanced DC production of IL-6. Here we explored further phenotypic changes in Blimp1-deficient DCs, the molecular mechanism underlying th...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561813/ https://ncbi.nlm.nih.gov/pubmed/23298838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64712 |
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