Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis

MicroRNAs (miRNAs) have been shown to be dysregulated in virus-related cancers; however, miRNA regulation of virus-related cancer development and progression remains poorly understood. Here, we report that miR-148a is repressed by hepatitis B virus (HBV) X protein (HBx) to promote cancer growth and...

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Detalhes bibliográficos
Principais autores: Xu, Xiaojie, Fan, Zhongyi, Kang, Lei, Han, Juqiang, Jiang, Chengying, Zheng, Xiaofei, Zhu, Ziman, Jiao, Huabo, Lin, Jing, Jiang, Kai, Ding, Lihua, Zhang, Hao, Cheng, Long, Fu, Hanjiang, Song, Yi, Jiang, Ying, Liu, Jiahong, Wang, Rongfu, Du, Nan, Ye, Qinong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561812/
https://ncbi.nlm.nih.gov/pubmed/23321675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64265
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