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Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation

Embryonic stem (ES) cells hold great promise with respect to their potential to be differentiated into desired cell types. Of interest are organs derived from the definitive endoderm, such as the pancreas and liver, and animal studies have revealed an essential role for Nodal in development of the d...

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Detalhes bibliográficos
Main Authors: Chen, Alice E., Borowiak, Malgorzata, Sherwood, Richard I., Kweudjeu, Anastasie, Melton, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561793/
https://ncbi.nlm.nih.gov/pubmed/23293299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.085431
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