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The energetic difference between synthesis of correct and incorrect base pairs accounts for highly accurate DNA replication
To better understand the energetics of accurate DNA replication, we directly measured ΔG(O) for the incorporation of a nucleotide into elongating dsDNA in solution (ΔG(O)(incorporation)). Direct measurements of the energetic difference between synthesis of correct and incorrect base pairs found it t...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561758/ https://ncbi.nlm.nih.gov/pubmed/23316816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja309866m |
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