Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells

Natural killer (NK) cells are involved in innate immune responses and play a major role in tumor surveillance and in defense against viruses. Human NK cells recognize human leukocyte antigen (HLA) class I molecules via surface receptors [killer immunoglobulin-like receptor (KIR) and NKG2A] deliverin...

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Autors principals: Locatelli, Franco, Pende, Daniela, Mingari, Maria C., Bertaina, Alice, Falco, Michela, Moretta, Alessandro, Moretta, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561663/
https://ncbi.nlm.nih.gov/pubmed/23378843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00015
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