Specificity Protein 1 (Sp1)-dependent Activation of the Synapsin I Gene (SYN1) Is Modulated by RE1-silencing Transcription Factor (REST) and 5′-Cytosine-Phosphoguanine (CpG) Methylation

The development and function of the nervous system are directly dependent on a well defined pattern of gene expression. Indeed, perturbation of transcriptional activity or epigenetic modifications of chromatin can dramatically influence neuronal phenotypes. The phosphoprotein synapsin I (Syn I) play...

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Hlavní autoři: Paonessa, Francesco, Latifi, Shahrzad, Scarongella, Helena, Cesca, Fabrizia, Benfenati, Fabio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561544/
https://ncbi.nlm.nih.gov/pubmed/23250796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399782
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