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Impact of Antibodies to Infliximab on Clinical Outcomes and Serum Infliximab Levels in Patients With Inflammatory Bowel Disease (IBD): A Meta-Analysis

OBJECTIVES: Antibodies to infliximab (ATIs) have been associated with loss of clinical response and lower serum infliximab (IFX) levels in some studies of patients with inflammatory bowel disease (IBD). This has important implications for patient management and development of novel biologic therapie...

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Autori principali: Nanda, Kavinderjit S., Cheifetz, Adam S., Moss, Alan C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561464/
https://ncbi.nlm.nih.gov/pubmed/23147525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2012.363
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