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Signaling Pathways of ESE-16, an Antimitotic and Anticarbonic Anhydrase Estradiol Analog, in Breast Cancer Cells

The aim of this study was to characterize the in vitro action of 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) on non-tumorigenic MCF-12A, tumorigenic MCF-7 and metastatic MDA-MB-231 breast cancer cells. ESE-16 is able to inhibit the activity of a carbonic anhydrase II and a mimic of ca...

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Detalhes bibliográficos
Main Authors: Stander, Barend Andre, Joubert, Fourie, Tu, Chingkuang, Sippel, Katherine H., McKenna, Robert, Joubert, Annie Margaretha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561402/
https://ncbi.nlm.nih.gov/pubmed/23382857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053853
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