The MAPK Pathway Signals Telomerase Modulation in Response to Isothiocyanate-Induced DNA Damage of Human Liver Cancer Cells

4-methylthiobutyl isothiocyanate (MTBITC), an aliphatic, sulphuric compound from Brassica vegetables, possesses in vitro and in vivo antitumor activity. Recently we demonstrated the potent growth inhibitory potential of the DNA damaging agent MTBITC in human liver cancer cells. Here we now show that...

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Bibliographic Details
Main Authors: Lamy, Evelyn, Herz, Corinna, Lutz-Bonengel, Sabine, Hertrampf, Anke, Márton, Melinda-Rita, Mersch-Sundermann, Volker
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561400/
https://ncbi.nlm.nih.gov/pubmed/23382840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053240
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