Over-Expressing Mitofusin-2 in Healthy Mature Mammalian Skeletal Muscle Does Not Alter Mitochondrial Bioenergetics

The role of mitofusin-2 (MFN-2) in regulating mitochondrial dynamics has been well-characterized in lower order eukaryotic cell lines through the complete ablation of MFN-2 protein. However, to support the contractile function of mature skeletal muscle, the subcellular architecture and constituent p...

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Autores principales: Lally, James S. V., Herbst, Eric A. F., Matravadia, Sarthak, Maher, Amy C., Perry, Christopher G. R., Ventura-Clapier, Renée, Holloway, Graham P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561349/
https://ncbi.nlm.nih.gov/pubmed/23383258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055660
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