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Class II HDAC Inhibition Hampers Hepatic Stellate Cell Activation by Induction of MicroRNA-29
BACKGROUND: The conversion of a quiescent vitamin A storing hepatic stellate cell (HSC) to a matrix producing, contractile myofibroblast-like activated HSC is a key event in the onset of liver disease following injury of any aetiology. Previous studies have shown that class I histone deacetylases (H...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561334/ https://ncbi.nlm.nih.gov/pubmed/23383282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055786 |
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