High Dose Zinc Supplementation Induces Hippocampal Zinc Deficiency and Memory Impairment with Inhibition of BDNF Signaling

Zinc ions highly concentrate in hippocampus and play a key role in modulating spatial learning and memory. At a time when dietary fortification and supplementation of zinc have increased the zinc consuming level especially in the youth, the toxicity of zinc overdose on brain function was underestima...

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Detalhes bibliográficos
Main Authors: Yang, Yang, Jing, Xiao-Peng, Zhang, Shou-Peng, Gu, Run-Xia, Tang, Fang-Xu, Wang, Xiu-Lian, Xiong, Yan, Qiu, Mei, Sun, Xu-Ying, Ke, Dan, Wang, Jian-Zhi, Liu, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561272/
https://ncbi.nlm.nih.gov/pubmed/23383172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055384
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