Aberrant methylation of the M-type phospholipase A(2) receptor gene in leukemic cells

BACKGROUND: The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the PLA2R1 gene in Jurkat and U937 leukemic cell lines and its methylation in patients with myelodysplas...

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Autors principals: Menschikowski, Mario, Platzbecker, Uwe, Hagelgans, Albert, Vogel, Margot, Thiede, Christian, Schönefeldt, Claudia, Lehnert, Renate, Eisenhofer, Graeme, Siegert, Gabriele
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561142/
https://ncbi.nlm.nih.gov/pubmed/23217014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-576
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