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Phenome-Wide Association Study (PheWAS) for Detection of Pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

Using a phenome-wide association study (PheWAS) approach, we comprehensively tested genetic variants for association with phenotypes available for 70,061 study participants in the Population Architecture using Genomics and Epidemiology (PAGE) network. Our aim was to better characterize the genetic a...

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Main Authors: Pendergrass, Sarah A., Brown-Gentry, Kristin, Dudek, Scott, Frase, Alex, Torstenson, Eric S., Goodloe, Robert, Ambite, Jose Luis, Avery, Christy L., Buyske, Steve, Bůžková, Petra, Deelman, Ewa, Fesinmeyer, Megan D., Haiman, Christopher A., Heiss, Gerardo, Hindorff, Lucia A., Hsu, Chu-Nan, Jackson, Rebecca D., Kooperberg, Charles, Le Marchand, Loic, Lin, Yi, Matise, Tara C., Monroe, Kristine R., Moreland, Larry, Park, Sungshim L., Reiner, Alex, Wallace, Robert, Wilkens, Lynn R., Crawford, Dana C., Ritchie, Marylyn D.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561060/
https://ncbi.nlm.nih.gov/pubmed/23382687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003087
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