Phenome-Wide Association Study (PheWAS) for Detection of Pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

Using a phenome-wide association study (PheWAS) approach, we comprehensively tested genetic variants for association with phenotypes available for 70,061 study participants in the Population Architecture using Genomics and Epidemiology (PAGE) network. Our aim was to better characterize the genetic a...

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Main Authors: Pendergrass, Sarah A., Brown-Gentry, Kristin, Dudek, Scott, Frase, Alex, Torstenson, Eric S., Goodloe, Robert, Ambite, Jose Luis, Avery, Christy L., Buyske, Steve, Bůžková, Petra, Deelman, Ewa, Fesinmeyer, Megan D., Haiman, Christopher A., Heiss, Gerardo, Hindorff, Lucia A., Hsu, Chu-Nan, Jackson, Rebecca D., Kooperberg, Charles, Le Marchand, Loic, Lin, Yi, Matise, Tara C., Monroe, Kristine R., Moreland, Larry, Park, Sungshim L., Reiner, Alex, Wallace, Robert, Wilkens, Lynn R., Crawford, Dana C., Ritchie, Marylyn D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561060/
https://ncbi.nlm.nih.gov/pubmed/23382687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003087
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