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Low dose morphine adjuvant therapy for enhanced efficacy of antipsychotic drug action: Potential involvement of endogenous morphine in the pathophysiology of schizophrenia

Major thematic threads linking extensive preclinical and clinical efforts have established a working mechanistic scheme whereby atypical antipsychotic drugs ameliorate negative DSM IV diagnostic criteria by effecting relatively potent blockade of serotonin (5-HT)(2A) receptors coupled with weaker an...

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Autors principals: Stefano, George B., Králíčková, Milena, Ptacek, Radek, Kuzelova, Hana, Esch, Tobias, Kream, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560770/
https://ncbi.nlm.nih.gov/pubmed/22739740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.883192
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