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Nod1 Is an Essential Signal Transducer in Intestinal Epithelial Cells Infected with Bacteria That Avoid Recognition by Toll-Like Receptors

The transcription factor NF-κB in human intestinal epithelial cells plays a central role in regulating genes that govern the onset of mucosal inflammatory responses following intestinal microbial infection. Nod1 is a cytosolic pattern recognition receptor in mammalian cells that senses components of...

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Detalhes bibliográficos
Main Authors: Kim, Jae Gyu, Lee, Sung Joong, Kagnoff, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356064/
https://ncbi.nlm.nih.gov/pubmed/14977954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1487-1495.2004
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