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Evaluation of a candidate anti-arthritic drug using the mouse collagen antibody induced arthritis model and clinically relevant biomarkers

The most rigorous scenario for testing a candidate rheumatoid arthritis therapeutic would be to use clinically relevant biomarkers and readouts to monitor disease development in an animal model that has a mechanism of disease that reflects the human condition. Treatment should begin when the full sp...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bender, Andrew T, Spyvee, Mark, Satoh, Takashi, Gershman, Benjamin, Teceno, Tyler, Burgess, Laurette, Kumar, Vipul, Wu, Yin, Yang, Hua, Ding, Yueyun, Akare, Sandeep, Chen, Qian
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: e-Century Publishing Corporation 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560477/
https://ncbi.nlm.nih.gov/pubmed/23390569
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