Brain angiotensin and dopaminergic degeneration: relevance to Parkinson’s disease

The pathogenic mechanism of Parkinson’s disease (PD) appears to be multifactorial. However, oxidative stress and neuroinflammation, including activation of NADPH-dependent oxidases, play a major role in the progression of dopaminergic cell death. The renin-angiotensin system (RAS) was described as a...

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Bibliographic Details
Main Authors: Labandeira-Garcia, Jose L, Rodriguez-Pallares, Jannette, Rodríguez-Perez, Ana I, Garrido-Gil, Pablo, Villar-Cheda, Begoña, Valenzuela, Rita, Guerra, Maria J
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560470/
https://ncbi.nlm.nih.gov/pubmed/23383395
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