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Impacts of sarA and agr in Staphylococcus aureus Strain Newman on Fibronectin-Binding Protein A Gene Expression and Fibronectin Adherence Capacity In Vitro and in Experimental Infective Endocarditis

We investigated the impacts of sarA and agr on fnbA expression and fibronectin-binding capacity in Staphylococcus aureus in vitro and in experimental endocarditis. Although sarA up-regulated and agr down-regulated both fnbA expression and fibronectin binding in vitro and in vivo, fnbA expression was...

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Udgivet i:Infect Immun
Principais autores: Xiong, Yan-Qiong, Bayer, Arnold S., Yeaman, Michael R., van Wamel, Willem, Manna, Adhar C., Cheung, Ambrose L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14977998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.3.1832-1836.2004
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