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Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease

Inflammatory lesions, ischemic tissues or solid tumors are characterized by the occurrence of severe tissue hypoxia within the diseased tissue. Subsequent stabilization of hypoxia-inducible transcription factors – particularly of hypoxia-inducible factor 1α (HIF1A) - results in significant alteratio...

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Detalhes bibliográficos
Main Authors: Poth, Jens M., Brodsky, Kelley, Ehrentraut, Heidi, Grenz, Almut, Eltzschig, Holger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560301/
https://ncbi.nlm.nih.gov/pubmed/23263788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0988-7
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