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Fast and accurate haplotype frequency estimation for large haplotype vectors from pooled DNA data
BACKGROUND: Typically, the first phase of a genome wide association study (GWAS) includes genotyping across hundreds of individuals and validation of the most significant SNPs. Allelotyping of pooled genomic DNA is a common approach to reduce the overall cost of the study. Knowledge of haplotype str...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560217/ https://ncbi.nlm.nih.gov/pubmed/23110720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-13-94 |
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