Effects of over-expression of TLR2 in transgenic goats on pathogen clearance and role of up-regulation of lysozyme secretion and infiltration of inflammatory cells

BACKGROUND: Toll-like receptor 2 (TLR2) is important to host recognition of invading gram-positive microbes. In goats, these microbes can cause serious mastitis, anthrax, tetanus, and other problems. Transgenic goats constitutively over-expressing TLR2 in many tissues serve as a suitable model for t...

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Main Authors: Deng, Shoulong, Yu, Kun, Zhang, Baolu, Yao, Yuchang, Liu, Yufeng, He, Haijuan, Zhang, Hongtao, Cui, Maosheng, Fu, Juncai, Lian, Zhengxing, Li, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560201/
https://ncbi.nlm.nih.gov/pubmed/23082910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-8-196
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