Heterozygous Toll-Like Receptor 2 Polymorphism Does Not Affect Lipoteichoic Acid-Induced Chemokine and Inflammatory Responses

While transfection of tlr2 conveyed responsiveness to lipoteichoic acid (LTA), the Arg753Gln polymorphic gene could not. LTA induced a stronger chemokine and anti-inflammatory response than lipopolysaccharides did. Blood from heterozygous polymorphic and wild-type donors reacted uniformly to LTA and...

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Détails bibliographiques
Auteurs principaux: von Aulock, Sonja, Schröder, Nicolas W. J., Traub, Stephanie, Gueinzius, Katja, Lorenz, Eva, Hartung, Thomas, Schumann, Ralf R., Hermann, Corinna
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Host Response and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC356018/
https://ncbi.nlm.nih.gov/pubmed/14977997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1828-1831.2004
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