Mycobacterial Purified Protein Derivatives Stimulate Innate Immunity: Malawians Show Enhanced Tumor Necrosis Factor Alpha, Interleukin-1β (IL-1β), and IL-10 Responses Compared to Those of Adolescents in the United Kingdom

To investigate the role of innate immunity in variable efficacy of Mycobacterium bovis BCG vaccination in Malawi and the United Kingdom, we examined 24-h tumor necrosis factor alpha, interleukin-1β (IL-1β), and IL-10 responses to mycobacterial purified protein derivatives (PPDs). The rank order in s...

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Bibliografiske detaljer
Main Authors: Weir, Rosemary E., Black, Gillian F., Dockrell, Hazel M., Floyd, Sian, Fine, Paul E. M., Chaguluka, Steven D., Stenson, Sally, King, Elizabeth, Nazareth, Bernadette, Warndorff, David K., Ngwira, Bagrey, Crampin, Amelia C., Mwaungulu, Lorren, Sichali, Lifted, Jarman, Elizabeth, Donovan, Linda, Blackwell, Jenefer M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC356017/
https://ncbi.nlm.nih.gov/pubmed/14977992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1807-1811.2004
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