Identification of srv, a PrfA-Like Regulator of Group A Streptococcus That Influences Virulence

We have identified a Crp/Fnr-like transcriptional regulator of Streptococcus pyogenes that when inactivated attenuates virulence. The gene, named srv for streptococcal regulator of virulence, encodes a 240-amino-acid protein with 53% amino acid similarity to PrfA, a transcriptional activator of viru...

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Detalles Bibliográficos
Main Authors: Reid, Sean D., Montgomery, Alison G., Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC355993/
https://ncbi.nlm.nih.gov/pubmed/14977990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1799-1803.2004
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