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The Klebsiella pneumoniae O Antigen Contributes to Bacteremia and Lethality during Murine Pneumonia

Bacterial surface carbohydrates are important pathogenic factors in gram-negative pneumonia infections. Among these factors, O antigen has been reported to protect pathogens against complement-mediated killing. To examine further the role of O antigen, we insertionally inactivated the gene encoding...

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Udgivet i:Infect Immun
Principais autores: Shankar-Sinha, Sunita, Valencia, Gabriel A., Janes, Brian K., Rosenberg, Jessica K., Whitfield, Chris, Bender, Robert A., Standiford, Ted J., Younger, John G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14977947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.3.1423-1430.2004
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