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Metabolites of Ginger Component [6]-Shogaol Remain Bioactive in Cancer Cells and Have Low Toxicity in Normal Cells: Chemical Synthesis and Biological Evaluation

Our previous study found that [6]-shogaol, a major bioactive component in ginger, is extensively metabolized in cancer cells and in mice. It is unclear whether these metabolites retain bioactivity. The aim of the current study is to synthesize the major metabolites of [6]-shogaol and evaluate their...

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Detalhes bibliográficos
Main Authors: Zhu, Yingdong, Warin, Renaud F., Soroka, Dominique N., Chen, Huadong, Sang, Shengmin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559867/
https://ncbi.nlm.nih.gov/pubmed/23382939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054677
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