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Differential Localization of the Two T. brucei Poly(A) Binding Proteins to the Nucleus and RNP Granules Suggests Binding to Distinct mRNA Pools

The number of paralogs of proteins involved in translation initiation is larger in trypanosomes than in yeasts or many metazoan and includes two poly(A) binding proteins, PABP1 and PABP2, and four eIF4E variants. In many cases, the paralogs are individually essential and are thus unlikely to have re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kramer, Susanne, Bannerman-Chukualim, Bridget, Ellis, Louise, Boulden, Elizabeth A., Kelly, Steve, Field, Mark C., Carrington, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559699/
https://ncbi.nlm.nih.gov/pubmed/23382864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054004
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